prfC protein (Prochlorococcus marinus MIT9312)

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prfC

Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (545 aa)

Predicted Functional Partners:

rpmA

0.877

rplT

0.857

rplL

0.852

rplS

0.852

rpmF

0.849

rpmG

0.841

rplI2

0.828

rplU

0.819

rplQ

0.819

rpl36

0.814

Your Current Organism:

Prochlorococcus marinus MIT9312

NCBI taxonomy Id: 74546
Other names: P. marinus str. MIT 9312, Prochlorococcus marinus str. MIT 9312, Prochlorococcus sp. MIT 9312, Prochlorococcus sp. MIT9312

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
prfC	rpl36	PMT9312_0663	PMT9312_1815	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	0.814
prfC	rplI2	PMT9312_0663	PMT9312_1765	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L9P; Binds to the 23S rRNA.	0.828
prfC	rplL	PMT9312_0663	PMT9312_0203	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.852
prfC	rplQ	PMT9312_0663	PMT9312_1627	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L17P; Alternative locus ID: P9312_17771.	0.819
prfC	rplS	PMT9312_0663	PMT9312_0475	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.852
prfC	rplT	PMT9312_0663	PMT9312_1754	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.857
prfC	rplU	PMT9312_0663	PMT9312_1442	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.819
prfC	rpmA	PMT9312_0663	PMT9312_1443	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L27P; Alternative locus ID: P9312_15641; Belongs to the bacterial ribosomal protein bL27 family.	0.877
prfC	rpmF	PMT9312_0663	PMT9312_0947	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L32P; Alternative locus ID: P9312_10111; Belongs to the bacterial ribosomal protein bL32 family.	0.849
prfC	rpmG	PMT9312_0663	PMT9312_0931	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L33P; Alternative locus ID: P9312_09891; Belongs to the bacterial ribosomal protein bL33 family.	0.841
rpl36	prfC	PMT9312_1815	PMT9312_0663	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	0.814
rpl36	rplI2	PMT9312_1815	PMT9312_1765	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L9P; Binds to the 23S rRNA.	0.976
rpl36	rplL	PMT9312_1815	PMT9312_0203	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.994
rpl36	rplQ	PMT9312_1815	PMT9312_1627	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L17P; Alternative locus ID: P9312_17771.	0.998
rpl36	rplS	PMT9312_1815	PMT9312_0475	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.993
rpl36	rplT	PMT9312_1815	PMT9312_1754	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.992
rpl36	rplU	PMT9312_1815	PMT9312_1442	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.996
rpl36	rpmA	PMT9312_1815	PMT9312_1443	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L27P; Alternative locus ID: P9312_15641; Belongs to the bacterial ribosomal protein bL27 family.	0.992
rpl36	rpmF	PMT9312_1815	PMT9312_0947	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L32P; Alternative locus ID: P9312_10111; Belongs to the bacterial ribosomal protein bL32 family.	0.994
rpl36	rpmG	PMT9312_1815	PMT9312_0931	50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.	LSU ribosomal protein L33P; Alternative locus ID: P9312_09891; Belongs to the bacterial ribosomal protein bL33 family.	0.992

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