| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABB49320.1 | gyrA | PMT9312_0259 | PMT9312_1074 | Competence/damage-inducible protein cinA; Alternative locus ID: P9312_02671; Belongs to the CinA family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.523 |
| ABB49320.1 | gyrB | PMT9312_0259 | PMT9312_1727 | Competence/damage-inducible protein cinA; Alternative locus ID: P9312_02671; Belongs to the CinA family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.531 |
| ABB49320.1 | polA | PMT9312_0259 | PMT9312_1236 | Competence/damage-inducible protein cinA; Alternative locus ID: P9312_02671; Belongs to the CinA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.619 |
| ABB49575.1 | gyrA | PMT9312_0514 | PMT9312_1074 | Signal peptidase I, Serine peptidase, MEROPS family S26A; Alternative locus ID: P9312_05391; Belongs to the peptidase S26 family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.576 |
| ABB49575.1 | nusA | PMT9312_0514 | PMT9312_1585 | Signal peptidase I, Serine peptidase, MEROPS family S26A; Alternative locus ID: P9312_05391; Belongs to the peptidase S26 family. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.501 |
| ABB49575.1 | rpoA | PMT9312_0514 | PMT9312_1628 | Signal peptidase I, Serine peptidase, MEROPS family S26A; Alternative locus ID: P9312_05391; Belongs to the peptidase S26 family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.591 |
| ABB50132.1 | ABB50134.1 | PMT9312_1073 | PMT9312_1075 | IMP dehydrogenase related 2; Alternative locus ID: P9312_11581. | Lycopene cyclase (CrtL-type); Alternative locus ID: P9312_11601. | 0.579 |
| ABB50132.1 | guaA | PMT9312_1073 | PMT9312_0037 | IMP dehydrogenase related 2; Alternative locus ID: P9312_11581. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.980 |
| ABB50132.1 | gyrA | PMT9312_1073 | PMT9312_1074 | IMP dehydrogenase related 2; Alternative locus ID: P9312_11581. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.639 |
| ABB50134.1 | ABB50132.1 | PMT9312_1075 | PMT9312_1073 | Lycopene cyclase (CrtL-type); Alternative locus ID: P9312_11601. | IMP dehydrogenase related 2; Alternative locus ID: P9312_11581. | 0.579 |
| ABB50134.1 | gyrA | PMT9312_1075 | PMT9312_1074 | Lycopene cyclase (CrtL-type); Alternative locus ID: P9312_11601. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.758 |
| guaA | ABB50132.1 | PMT9312_0037 | PMT9312_1073 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase related 2; Alternative locus ID: P9312_11581. | 0.980 |
| guaA | gyrA | PMT9312_0037 | PMT9312_1074 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.488 |
| guaA | gyrB | PMT9312_0037 | PMT9312_1727 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.552 |
| guaA | nusA | PMT9312_0037 | PMT9312_1585 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.592 |
| guaA | pheT | PMT9312_0037 | PMT9312_0930 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta subunit; Alternative locus ID: P9312_09881; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.923 |
| guaA | polA | PMT9312_0037 | PMT9312_1236 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.681 |
| guaA | rpoA | PMT9312_0037 | PMT9312_1628 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.903 |
| gyrA | ABB49320.1 | PMT9312_1074 | PMT9312_0259 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Competence/damage-inducible protein cinA; Alternative locus ID: P9312_02671; Belongs to the CinA family. | 0.523 |
| gyrA | ABB49575.1 | PMT9312_1074 | PMT9312_0514 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Signal peptidase I, Serine peptidase, MEROPS family S26A; Alternative locus ID: P9312_05391; Belongs to the peptidase S26 family. | 0.576 |
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