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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABB50361.1Pyruvate dehydrogenase (lipoamide); Alternative locus ID: P9312_14211. (347 aa)    
Predicted Functional Partners:
ABB49929.1
Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
ABB50362.1
Pyruvate dehydrogenase (lipoamide); Alternative locus ID: P9312_14221.
 0.999
ABB49461.1
Dihydrolipoamide acetyltransferase component (E2); Similar to other related enzymes; Alternative locus ID: P9312_04251.
 
 0.998
ABB50454.1
Dihydrolipoamide dehydrogenase; Alternative locus ID: P9312_15151.
 
 
 0.970
ABB49948.1
Pyruvate kinase; Alternative locus ID: P9312_09461; Belongs to the pyruvate kinase family.
  
 
 0.943
pdhA
Pyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 
0.920
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
   
 
 0.838
ABB49849.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
    
 0.831
ABB50764.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.827
pgi
Glucose-6-phosphate isomerase; Alternative locus ID: P9312_09681; Belongs to the GPI family.
     
 0.826
Your Current Organism:
Prochlorococcus marinus MIT9312
NCBI taxonomy Id: 74546
Other names: P. marinus str. MIT 9312, Prochlorococcus marinus str. MIT 9312, Prochlorococcus sp. MIT 9312, Prochlorococcus sp. MIT9312
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