STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THRCLA_02395Uncharacterized protein. (586 aa)    
Predicted Functional Partners:
THRCLA_22060
GMP synthase, glutamine-hydrolyzing.
  
 
 0.695
THRCLA_00735
Cysteine protease family C26.
    
 0.687
THRCLA_03205
Bifunctional purine biosynthesis protein PURH.
    
 0.645
THRCLA_20512
Tyrosine phosphatase type IVA protein 1.
    
 
 0.607
THRCLA_10579
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.591
THRCLA_02846
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.536
THRCLA_09231
Adenine phosphoribosyltransferase.
  
 
 0.498
THRCLA_07758
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.475
THRCLA_02247
Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.
    
 0.475
THRCLA_20566
AB hydrolase-1 domain-containing protein.
  
 
  0.404
Your Current Organism:
Thraustotheca clavata
NCBI taxonomy Id: 74557
Other names: T. clavata
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.