node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | THRCLA_00954 | A0A1W0A0Z4 | A0A1W0A9R9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | ATPase_AAA_core domain-containing protein. | 0.998 |
MCM7 | THRCLA_02323 | A0A1W0A0Z4 | A0A1W0A5L4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM6; Belongs to the MCM family. | 0.996 |
MCM7 | THRCLA_02864 | A0A1W0A0Z4 | A0A1W0A3T8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.996 |
MCM7 | THRCLA_04677 | A0A1W0A0Z4 | A0A1V9ZY87 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.994 |
MCM7 | THRCLA_04746 | A0A1W0A0Z4 | A0A1V9ZY40 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the HSF family. | 0.999 |
MCM7 | THRCLA_05835 | A0A1W0A0Z4 | A0A1V9ZS95 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit. | 0.996 |
MCM7 | THRCLA_06153 | A0A1W0A0Z4 | A0A1V9ZQG8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM3; Belongs to the MCM family. | 0.999 |
MCM7 | THRCLA_08040 | A0A1W0A0Z4 | A0A1V9ZAJ5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | THRCLA_08220 | A0A1W0A0Z4 | A0A1V9Z887 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.987 |
MCM7 | THRCLA_11545 | A0A1W0A0Z4 | A0A1V9Y7D2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | ORC_WH_C domain-containing protein. | 0.987 |
THRCLA_00954 | MCM7 | A0A1W0A9R9 | A0A1W0A0Z4 | ATPase_AAA_core domain-containing protein. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
THRCLA_00954 | THRCLA_02323 | A0A1W0A9R9 | A0A1W0A5L4 | ATPase_AAA_core domain-containing protein. | DNA replication licensing factor MCM6; Belongs to the MCM family. | 0.990 |
THRCLA_00954 | THRCLA_02864 | A0A1W0A9R9 | A0A1W0A3T8 | ATPase_AAA_core domain-containing protein. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
THRCLA_00954 | THRCLA_04677 | A0A1W0A9R9 | A0A1V9ZY87 | ATPase_AAA_core domain-containing protein. | Uncharacterized protein. | 0.998 |
THRCLA_00954 | THRCLA_04746 | A0A1W0A9R9 | A0A1V9ZY40 | ATPase_AAA_core domain-containing protein. | DNA helicase; Belongs to the HSF family. | 0.999 |
THRCLA_00954 | THRCLA_05835 | A0A1W0A9R9 | A0A1V9ZS95 | ATPase_AAA_core domain-containing protein. | Origin recognition complex subunit. | 0.996 |
THRCLA_00954 | THRCLA_06153 | A0A1W0A9R9 | A0A1V9ZQG8 | ATPase_AAA_core domain-containing protein. | DNA replication licensing factor MCM3; Belongs to the MCM family. | 0.998 |
THRCLA_00954 | THRCLA_08040 | A0A1W0A9R9 | A0A1V9ZAJ5 | ATPase_AAA_core domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.998 |
THRCLA_00954 | THRCLA_08220 | A0A1W0A9R9 | A0A1V9Z887 | ATPase_AAA_core domain-containing protein. | Uncharacterized protein. | 0.999 |
THRCLA_00954 | THRCLA_11545 | A0A1W0A9R9 | A0A1V9Y7D2 | ATPase_AAA_core domain-containing protein. | ORC_WH_C domain-containing protein. | 0.999 |