STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (303 aa)    
Predicted Functional Partners:
thrC
Threonine synthase.
 
 0.998
AFD25018.1
Homoserine dehydrogenase.
 
 0.996
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.911
AFD25758.1
Hypothetical protein.
     
  0.900
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.895
lysC
Aspartokinase; Belongs to the aspartokinase family.
 
 
 0.857
ilvE
Branched-chain amino acid aminotransferase II; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.853
sdhB-2
L-serine dehydratase, iron-sulfur-dependent, beta subunit.
  
 
 0.836
AFD26299.1
L-serine dehydratase, alpha subunit.
  
 
 0.836
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
  
  0.823
Your Current Organism:
Deinococcus gobiensis
NCBI taxonomy Id: 745776
Other names: D. gobiensis I-0, Deinococcus gobiensis I-0, Deinococcus gobiensis str. I-0, Deinococcus gobiensis strain I-0, Deinococcus sp. I-0
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