STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A087ZWM0NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family. (591 aa)    
Predicted Functional Partners:
LOC552386
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
    
 0.992
Mms19
Uncharacterized protein.
    
 0.952
A0A088A1G0
FeS_assembly_P domain-containing protein.
    
 0.929
A0A087ZQ55
Fe_hyd_SSU domain-containing protein; Belongs to the NARF family.
    
 0.917
Ciao1
Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
     
 0.904
Cyp4g11
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
  
 
 0.902
A0A088A7F3
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
  
 
 0.886
LOC409195
FeS_assembly_P domain-containing protein.
    
 0.798
CYP6AS17
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
  
 
 0.796
Cbs
PALP domain-containing protein.
 
 
 0.784
Your Current Organism:
Apis mellifera
NCBI taxonomy Id: 7460
Other names: A. mellifera, Apis mellifica, European honey bee, Western honey bee, bee, honey bee, honeybee
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.