STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A088AED3Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (353 aa)    
Predicted Functional Partners:
A0A088ASG1
Uncharacterized protein.
  
 
 0.971
A0A088ACC5
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.935
A0A088ADD4
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.933
LOC412548
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.931
LOC412948
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.888
A0A088AK01
Uncharacterized protein.
  
 
 0.888
A0A088A9A5
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
    
 0.873
LOC409306
Transket_pyr domain-containing protein.
  
 0.832
A0A088AW58
TPP_enzyme_C domain-containing protein.
  
 0.812
A0A088A1S8
Uncharacterized protein; Belongs to the TPP enzyme family.
  
 0.787
Your Current Organism:
Apis mellifera
NCBI taxonomy Id: 7460
Other names: A. mellifera, Apis mellifica, European honey bee, Western honey bee, bee, honey bee, honeybee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.