node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A087ZX79 | A0A087ZZR0 | A0A087ZX79 | A0A087ZZR0 | XPGI domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.886 |
A0A087ZX79 | A0A088A1K3 | A0A087ZX79 | A0A088A1K3 | XPGI domain-containing protein. | ERCC4 domain-containing protein. | 0.924 |
A0A087ZX79 | A0A088A9L5 | A0A087ZX79 | A0A088A9L5 | XPGI domain-containing protein. | HRDC domain-containing protein. | 0.931 |
A0A087ZX79 | A0A088A9L6 | A0A087ZX79 | A0A088A9L6 | XPGI domain-containing protein. | Uncharacterized protein. | 0.931 |
A0A087ZX79 | A0A088AAW9 | A0A087ZX79 | A0A088AAW9 | XPGI domain-containing protein. | ERCC4 domain-containing protein. | 0.863 |
A0A087ZX79 | A0A088AQP8 | A0A087ZX79 | A0A088AQP8 | XPGI domain-containing protein. | DUF1767 domain-containing protein. | 0.821 |
A0A087ZX79 | LOC410571 | A0A087ZX79 | A0A087ZSA7 | XPGI domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.919 |
A0A087ZX79 | LOC725518 | A0A087ZX79 | A0A087ZYC4 | XPGI domain-containing protein. | Uncharacterized protein. | 0.960 |
A0A087ZX79 | LOC726757 | A0A087ZX79 | A0A087ZWB5 | XPGI domain-containing protein. | Uncharacterized protein. | 0.677 |
A0A087ZX79 | Rad51 | A0A087ZX79 | A0A088A022 | XPGI domain-containing protein. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. | 0.989 |
A0A087ZZR0 | A0A087ZX79 | A0A087ZZR0 | A0A087ZX79 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | XPGI domain-containing protein. | 0.886 |
A0A087ZZR0 | A0A088A1K3 | A0A087ZZR0 | A0A088A1K3 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | ERCC4 domain-containing protein. | 0.836 |
A0A087ZZR0 | A0A088A9L5 | A0A087ZZR0 | A0A088A9L5 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | HRDC domain-containing protein. | 0.945 |
A0A087ZZR0 | A0A088A9L6 | A0A087ZZR0 | A0A088A9L6 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Uncharacterized protein. | 0.945 |
A0A087ZZR0 | A0A088AAW9 | A0A087ZZR0 | A0A088AAW9 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | ERCC4 domain-containing protein. | 0.956 |
A0A087ZZR0 | A0A088AQP8 | A0A087ZZR0 | A0A088AQP8 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DUF1767 domain-containing protein. | 0.970 |
A0A087ZZR0 | LOC410571 | A0A087ZZR0 | A0A087ZSA7 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.979 |
A0A087ZZR0 | LOC725518 | A0A087ZZR0 | A0A087ZYC4 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Uncharacterized protein. | 0.962 |
A0A087ZZR0 | LOC726757 | A0A087ZZR0 | A0A087ZWB5 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Uncharacterized protein. | 0.999 |
A0A087ZZR0 | Rad51 | A0A087ZZR0 | A0A088A022 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. | 0.992 |