STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2P6RL06DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination; Belongs to the RecA family. RAD51 subfamily. (337 aa)    
Predicted Functional Partners:
A0A2P6REV8
Putative breast cancer type 2 susceptibility protein.
   
 0.897
A0A2P6R4M1
Putative DNA repair protein XRCC2.
   
 0.879
A0A2P6QKW5
Putative DNA helicase.
  
 0.855
A0A2P6QL44
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.855
A0A2P6QL45
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.855
A0A2P6QBE3
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.815
A0A2P6Q5U8
Putative aminoacyltransferase, E1 ubiquitin-activating enzyme.
   
 0.813
A0A2P6QW98
Putative DNA repair protein Rad50.
  
 0.784
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.761
A0A2P6PV07
Putative aminoacyltransferase, E1 ubiquitin-activating enzyme.
   
 0.751
Your Current Organism:
Rosa chinensis
NCBI taxonomy Id: 74649
Other names: China rose, R. chinensis, Rosa chinensis Jacq., Rosa indica auct., non L.
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