Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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A0A2P6SMD7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (380 aa)    
Predicted Functional Partners:
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
   0.708
A0A2P6RIE5
DNA helicase; Belongs to the MCM family.
    
   0.708
A0A2P6SPW8
Putative origin recognition complex, subunit 3.
    
   0.708
A0A2P6RG45
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
   0.661
A0A2P6P1F6
Putative winged helix-turn-helix DNA-binding domain, CDT1 Geminin-binding domain-containing protein.
    
   0.660
A0A2P6PPT0
Putative DNA helicase; Belongs to the MCM family.
    
   0.660
A0A2P6PPV6
Putative DNA helicase.
    
   0.660
A0A2P6PVD4
Putative winged helix-turn-helix DNA-binding domain, CDT1 Geminin-binding domain-containing protein.
    
   0.660
A0A2P6Q0C6
Putative origin recognition complex, subunit 2.
    
   0.660
A0A2P6Q0F8
Putative origin recognition complex, subunit 2.
    
   0.660
Your Current Organism:
Rosa chinensis
NCBI taxonomy Id: 74649
Other names: China rose, R. chinensis, Rosa chinensis Jacq., Rosa indica auct., non L.
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