STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE13702.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dps:DP0059 glycolate oxidase subunit (GlcD); PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase subunit glcD; IMG reference gene:2504783413; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (764 aa)    
Predicted Functional Partners:
AEE15043.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: aar:Acear_1800 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Cysteine-rich region, CCG; SPTR: Putative uncharacterized protein; IMG reference gene:2504784839; PFAM: Cysteine-rich domain.
 
 0.985
AEE15042.1
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: chy:CHY_0432 putative glycolate oxidase, GlcD subunit; PFAM: FAD linked oxidase, N-terminal; FAD-linked oxidase, C-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative glycolate oxidase, GlcD subunit; IMG reference gene:2504784838; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain.
  
  
 
0.928
AEE14558.1
Glyoxylate reductase; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: bmd:BMD_3518 glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; PRIAM: Glyoxylate reductase; SPTR: Glyoxylate reductase; IMG reference gene:2504784324; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
   
 0.916
AEE14487.1
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dhd:Dhaf_4518 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative uncharacterized protein; IMG reference gene:2504784250; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
  
  
 
0.908
AEE15044.1
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dhd:Dhaf_4518 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative uncharacterized protein; IMG reference gene:2504784840; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
  
  
 
0.907
AEE13910.1
Serine--pyruvate transaminase; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: bts:Btus_1044 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--pyruvate transaminase; SPTR: Aminotransferase class V; IMG reference gene:2504783631; PFAM: Aminotransferase class-V.
  
 
 0.905
AEE14658.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR006439:IPR005834; KEGG: dal:Dalk_1233 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: Similar to phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2504784426; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
    
 0.905
AEE14687.1
2-hydroxy-3-oxopropionate reductase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: rcu:RCOM_1211530 3-hydroxyisobutyrate dehydrogenase, putative; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: Putative uncharacterized protein; IMG reference gene:2504784463; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase.
    
  0.900
AEE13701.1
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: pmo:Pmob_0926 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; IMG reference gene:2504783412; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
  
    0.775
AEE13756.1
COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731; KEGG: chy:CHY_2477 electron transfer flavoprotein subunit alpha; PFAM: Electron transfer flavoprotein, alpha subunit, C-terminal; Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein, alpha subunit; IMG reference gene:2504783468; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain.
  
 
 0.753
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.