STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE13722.1Peroxiredoxin; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479; KEGG: cst:CLOST_2406 peroxiredoxin; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin, C-terminal; PRIAM: Peroxiredoxin; SPTR: Putative peroxiredoxin; IMG reference gene:2504783433; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family. (203 aa)    
Predicted Functional Partners:
AEE13761.1
InterPro IPR005243; KEGG: ckr:CKR_1590 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Redox-active disulphide protein 2; IMG reference gene:2504783473; TIGRFAM: small redox-active disulfide protein 2.
  
 0.924
AEE13723.1
Peptidase S16 lon domain protein; COGs: COG1067 ATP-dependent protease; InterPro IPR008269; KEGG: tye:THEYE_A1753 ATP-dependent protease La; PFAM: Peptidase S16, lon C-terminal; SPTR: ATP-dependent protease La; IMG reference gene:2504783434; PFAM: Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease.
       0.773
AEE14110.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027; KEGG: dma:DMR_17800 putative thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Putative thioredoxin reductase; IMG reference gene:2504783849; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.733
AEE14527.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982; KEGG: sfu:Sfum_3874 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: Thioredoxin reductase; IMG reference gene:2504784291; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
 
 0.733
AEE14383.1
CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001763; KEGG: afu:AF0400 NADH oxidase (NoxA-3); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: NADH oxidase (NoxA-3); IMG reference gene:2504784135; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.
  
  
 0.599
AEE14898.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: ferric-uptake regulator; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; IMG reference gene:2504784690; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
  
 0.594
AEE14990.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR005746:IPR013766; KEGG: thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; IMG reference gene:2504784784; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 0.524
AEE13721.1
SPTR: Putative uncharacterized protein; IMG reference gene:2504783432.
       0.512
AEE13720.1
MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: geo:Geob_2390 MgtC/SapB transporter; PFAM: MgtC/SapB transporter; SPTR: MgtC/SapB transporter; IMG reference gene:2504783431; PFAM: MgtC family.
     
 0.507
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.472
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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