STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE13795.1HNH endonuclease; COGs: COG1403 Restriction endonuclease; InterPro IPR002711:IPR003615; KEGG: syp:SYNPCC7002_A1573 restriction endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: Restriction endonuclease; IMG reference gene:2504783511; PFAM: HNH endonuclease. (165 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
    0.728
fdhD
Molybdopterin-guanine dinucleotide biosynthesis protein A; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
     0.504
AEE14839.1
WD40 repeat-containing protein; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680:IPR019781; KEGG: cyj:Cyan7822_6361 WD40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat; SPTR: WD40 repeat, subgroup; IMG reference gene:2504784628; PFAM: WD domain, G-beta repeat.
 
    0.445
AEE14411.1
Protein of unknown function DUF814; COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: ddf:DEFDS_0624 fibronectin/fibrinogen-binding protein; PFAM: Protein of unknown function DUF814; Fibronectin-binding A, N-terminal; SPTR: Fibronectin/fibrinogen-binding protein; manually curated; IMG reference gene:2504784165; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA).
 
     0.400
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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