STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE13814.1Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (182 aa)    
Predicted Functional Partners:
AEE15211.1
COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002650; KEGG: dau:Daud_1078 sulfate adenylyltransferase; PFAM: Sulphate adenylyltransferase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase; TIGRFAM: Sulphate adenylyltransferase; IMG reference gene:2504785017; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase.
 
 0.999
AEE15208.1
Adenylylsulfate reductase, alpha subunit; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR011803:IPR003953; KEGG: tye:THEYE_A1832 adenylylsulfate reductase subunit alpha; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: Adenylylsulfate reductase, alpha subunit; TIGRFAM: Adenylylsulphate reductase, alpha subunit; IMG reference gene:2504785014; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
    
 0.917
AEE15209.1
InterPro IPR011802:IPR001450; KEGG: cte:CT0864 adenylylsulfate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Adenylylsulfate reductase, beta subunit; TIGRFAM: Adenylylsulphate reductase, beta subunit; IMG reference gene:2504785015; PFAM: Adenosine-5'-phosphosulfate reductase beta subunit; TIGRFAM: adenosine phosphosulphate reductase, beta subunit.
  
 
 0.909
AEE14247.1
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: pth:PTH_1271 exopolyphosphatase-related proteins; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; manually curated; IMG reference gene:2504783990; PFAM: DHH family; DHHA1 domain.
   
 
  0.901
AEE14838.1
COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794:IPR008279; KEGG: tjr:TherJR_2325 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; PRIAM: Pyruvate kinase., Pyruvate, water dikinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504784627; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase.
    
 0.901
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
 
      0.900
AEE14430.1
COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795:IPR004161:IPR004160:IPR004541:IPR 005225; KEGG: dth:DICTH_0835 elongation factor Tu; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; SPTR: Elongation factor Tu 1; TIGRFAM: Translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; IMG reference gene:2504784189; PFAM: Elongation factor Tu C-terminal domain; Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: [...]
 
      0.900
AEE15087.1
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878:IPR003754; KEGG: slp:Slip_1426 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; IMG reference gene:2504784886; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin [...]
  
  
 0.847
AEE14894.1
ABC-type transporter, integral membrane subunit; COGs: COG0555 ABC-type sulfate transport system permease component; InterPro IPR000515; KEGG: tin:Tint_2168 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504784686; PFAM: Binding-protein-dependent transport system inner membrane component.
  
  
 0.787
AEE15035.1
COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR001926; KEGG: dth:DICTH_1733 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase A; TIGRFAM: Cysteine synthase K/M; IMG reference gene:2504784831; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases.
  
  
 0.730
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.