Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
AEE13849.1DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tte:TTE0651 cell wall biogenesis regulatory protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; IMG reference gene:2504783566; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (361 aa)    
Predicted Functional Partners:
AEE14701.1
Undecaprenyl-phosphate galactose phosphotransferase, WbaP; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017472:IPR017475:IPR003362; KEGG: hya:HY04AAS1_0831 undecaprenyl-phosphate galactose phosphotransferase, WbaP; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactosephosphotransferase; TIGRFAM: Undecaprenyl-phosphate galactose phosphotransferase, WbaP; Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; IMG reference gene:2504784478; PFAM: Bacteria [...]
  
 0.976
AEE14130.1
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: dth:DICTH_0431 oxidoreductase, Gfo/Idh/MocA family/transferase hexapeptide repeat protein; PFAM: Oxidoreductase, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504783869; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
 0.964
AEE14040.1
COGs: COG1216 glycosyltransferase; InterPro IPR013217:IPR001173; KEGG: hya:HY04AAS1_1576 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; Methyltransferase type 12; SPTR: Glycosyl transferase family 2; IMG reference gene:2504783774; PFAM: Methionine biosynthesis protein MetW; Glycosyl transferase family 2.
  
  
 0.747
AEE13848.1
Protein of unknown function DUF951; InterPro IPR009296; KEGG: bli:BL05397 hypothetical protein; PFAM: Protein of unknown function DUF951, bacterial; SPTR: Putative uncharacterized protein yyzM; IMG reference gene:2504783565; PFAM: Bacterial protein of unknown function (DUF951).
       0.701
AEE13948.1
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR006375:IPR005835:IPR001538; KEGG: mfs:MFS40622_0607 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase, type II, C-terminal; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; IMG reference gene:2504783672; PFAM: Nucleo [...]
  
  
 0.630
AEE13847.1
HemN domain protein; COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR010723:IPR006638; KEGG: pmx:PERMA_1838 putative oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative oxygen-independent coproporphyrinogen III oxidase; IMG reference gene:2504783564; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase.
  
  
 0.589
AEE13850.1
Phosphoesterase RecJ domain protein; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156; KEGG: cst:CLOST_1307 single-stranded-DNA-specific exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Putative single-stranded-DNA-specific exonuclease; IMG reference gene:2504783567; PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.
       0.584
lepA
GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.569
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
    0.535
AEE13705.1
Glucose-1-phosphate thymidyltransferase; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005908:IPR005835; KEGG: chy:CHY_0976 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate thymidylyltransferase; SPTR: Glucose-1-phosphate thymidylyltransferase; TIGRFAM: Glucose-1-phosphate thymidylyltransferase, short form; IMG reference gene:2504783416; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form.
  
  
 0.534
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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