STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE13879.1Protein of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: tjr:TherJR_1173 protein of unknown function DUF39; PFAM: Protein of unknown function DUF39; SPTR: Putative uncharacterized protein; IMG reference gene:2504783597; PFAM: Domain of unknown function DUF39. (384 aa)    
Predicted Functional Partners:
AEE13880.1
NIL domain-containing protein; InterPro IPR018449:IPR001450; KEGG: det:DET0920 iron-sulfur cluster-binding protein; PFAM: NIL domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504783598; PFAM: 4Fe-4S binding domain; NIL domain.
 
  
  0.994
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
  0.910
AEE14269.1
InterPro IPR001450; KEGG: apo:Arcpr_1028 RNA polymerase insert; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: DNA-directed RNA polymerase subunit D; IMG reference gene:2504784012; PFAM: 4Fe-4S binding domain.
     
  0.900
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.900
AEE14628.1
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: aar:Acear_1069 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase; IMG reference gene:2504784396; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
     
  0.900
metE
5-methyltetrahydropteroyltriglutamate-- homocysteinemethyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
  0.900
AEE13914.1
ApbE family lipoprotein; COGs: COG2122 conserved hypothetical protein; InterPro IPR003374; KEGG: deg:DehalGT_0764 ApbE family lipoprotein; PFAM: ApbE-like lipoprotein; SPTR: Putative uncharacterized protein; IMG reference gene:2504783635; PFAM: ApbE family.
 
   
 0.852
AEE15035.1
COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR001926; KEGG: dth:DICTH_1733 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase A; TIGRFAM: Cysteine synthase K/M; IMG reference gene:2504784831; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases.
    
  0.805
AEE13878.1
COGs: COG0527 Aspartokinase; InterPro IPR005260:IPR001341:IPR001048:IPR002912; KEGG: adg:Adeg_0884 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; IMG reference gene:2504783596; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
       0.791
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
       0.615
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.