STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE13927.1GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: pca:Pcar_2325 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: N-acetylglutamate synthase; manually curated; IMG reference gene:2504783649; PFAM: Acetyltransferase (GNAT) family; Belongs to the acetyltransferase family. (149 aa)    
Predicted Functional Partners:
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.970
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 0.950
argH
COGs: COG0165 Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; InterPro IPR009049:IPR000362; KEGG: dap:Dacet_2886 argininosuccinate lyase; PFAM: Fumarate lyase; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase; IMG reference gene:2504783865; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
 
  
 0.936
AEE14654.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: dae:Dtox_3997 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region; PRIAM: Glutamate dehydrogenase (NAD(P)(+)); SPTR: Glu/Leu/Phe/Val dehydrogenase; IMG reference gene:2504784422; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
  0.901
AEE14673.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: cst:CLOST_1222 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase class I and II; IMG reference gene:2504784442; PFAM: Aminotransferase class I and II.
     
  0.900
AEE14336.1
Nucleoside diphosphate pyrophosphatase; InterPro IPR000086:IPR004385; KEGG: amt:Amet_2521 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; TIGRFAM: Nucleoside diphosphate pyrophosphatase; IMG reference gene:2504784082; PFAM: NUDIX domain; TIGRFAM: nudix-type nucleoside diphosphatase, YffH/AdpP family; Belongs to the Nudix hydrolase family.
 
    0.729
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
       0.717
AEE13926.1
Sodium/calcium exchanger membrane region; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837; KEGG: drm:Dred_2521 sodium/calcium exchanger membrane region; PFAM: Sodium/calcium exchanger membrane region; SPTR: Sodium/calcium exchanger protein; IMG reference gene:2504783648; PFAM: Sodium/calcium exchanger protein.
       0.714
AEE13928.1
Phosphopantetheine-protein transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.682
AEE13929.1
Hypothetical protein; IMG reference gene:2504783651.
       0.682
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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