Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEE13977.1YibE/F family protein; COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: amt:Amet_0543 YibE/F family protein; PFAM: YibE/F-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504783708; PFAM: YibE/F-like protein. (381 aa)    
Predicted Functional Partners:
AEE13978.1
DNA integrity scanning, DisA, linker region; COGs: COG1623 nucleic-acid-binding protein (contains the HHH domain); InterPro IPR003390:IPR018906; KEGG: tjr:TherJR_0249 DNA integrity scanning, DisA, linker region; PFAM: DNA integrity scanning, DisA, linker region; DNA integrity scanning protein, DisA, N-terminal; SPTR: DNA integrity scanning, DisA, linker region; IMG reference gene:2504783709; PFAM: DisA bacterial checkpoint controller nucleotide-binding; DisA bacterial checkpoint controller linker region; Belongs to the DisA family.
       0.773
AEE13979.1
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.773
AEE13980.1
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR001943:IPR 013093:IPR019489; KEGG: cya:CYA_0656 Clp protease, ATP-binding subunit ClpC; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: Clp protease, ATP-binding subunit ClpC; IMG reference gene:2504783711; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; A [...]
       0.773
AEE13765.1
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: pth:PTH_0734 glutamate synthase domain-containing 2; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase domain 2; IMG reference gene:2504783480; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
       0.544
AEE13976.1
Hypothetical protein; IMG reference gene:2504783707; PFAM: PEGA domain.
       0.500
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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