STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE13992.1COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: tjr:TherJR_1676 pyruvate/ketoisovalerate oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: Pyruvate/ketoisovalerate oxidoreductase; IMG reference gene:2504783723; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. (180 aa)    
Predicted Functional Partners:
AEE13991.1
2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: tit:Thit_1912 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding; IMG reference gene:2504783722; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 0.999
AEE13990.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: kol:Kole_2160 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; IMG reference gene:2504783721; PFAM: domain.
 
 0.997
AEE14716.1
2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: toc:Toce_1203 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; IMG reference gene:2504784493; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
 0.996
AEE13989.1
InterPro IPR001450; KEGG: kol:Kole_2161 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; IMG reference gene:2504783720; PFAM: 4Fe-4S binding domain.
 
 
 0.995
AEE14522.1
COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766:IPR011896; KEGG: tye:THEYE_A0983 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoacid:ferredoxin oxidoreductase subunit beta; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; IMG reference gene:2504784286; PFAM: Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal [...]
 
 0.976
AEE14717.1
2-oxoglutarate synthase; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 2-oxoglutarate synthase; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; IMG reference gene:2504784494; PFAM: domain; Transketolase, C-terminal domain.
 
 0.960
AEE14521.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: mma:MM_0420 pyruvate synthase subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: Pyruvate synthase subunit alpha; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504784285; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:ac [...]
  
 0.950
AEE13988.1
KEGG: kol:Kole_2162 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504783719.
 
     0.936
AEE14715.1
2-oxoglutarate synthase; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: cst:CLOST_1471 2-oxoglutarate synthase subunit korc (2-ketoglutarate oxidoreductase gamma chain) (kor) (2-oxoglutarate-ferredoxin oxidoreductase subunit gamma); PFAM: Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate synthase subunit korC (2-ketoglutarate oxidoreductase gamma chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit gamma); IMG reference gene:2504784492; PFAM: [...]
  
  
 
0.923
AEE14718.1
InterPro IPR001450; KEGG: nth:Nther_1481 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; IMG reference gene:2504784495.
  
 
 0.922
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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