STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE14247.1Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: pth:PTH_1271 exopolyphosphatase-related proteins; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase-related proteins; manually curated; IMG reference gene:2504783990; PFAM: DHH family; DHHA1 domain. (319 aa)    
Predicted Functional Partners:
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.931
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.918
AEE13814.1
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
   
 
  0.901
AEE15208.1
Adenylylsulfate reductase, alpha subunit; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR011803:IPR003953; KEGG: tye:THEYE_A1832 adenylylsulfate reductase subunit alpha; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: Adenylylsulfate reductase, alpha subunit; TIGRFAM: Adenylylsulphate reductase, alpha subunit; IMG reference gene:2504785014; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
     
  0.900
AEE15209.1
InterPro IPR011802:IPR001450; KEGG: cte:CT0864 adenylylsulfate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Adenylylsulfate reductase, beta subunit; TIGRFAM: Adenylylsulphate reductase, beta subunit; IMG reference gene:2504785015; PFAM: Adenosine-5'-phosphosulfate reductase beta subunit; TIGRFAM: adenosine phosphosulphate reductase, beta subunit.
     
  0.900
AEE15211.1
COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002650; KEGG: dau:Daud_1078 sulfate adenylyltransferase; PFAM: Sulphate adenylyltransferase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase; TIGRFAM: Sulphate adenylyltransferase; IMG reference gene:2504785017; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase.
     
  0.900
AEE14249.1
Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: mtt:Ftrac_0781 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504783992; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.
 
     0.884
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
    0.741
rimP
Ribosome maturation factor rimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.633
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
       0.633
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.