STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
minCSeptum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (225 aa)    
Predicted Functional Partners:
AEE14320.1
Septum site-determining protein MinD; COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR002586:IPR010223; KEGG: ctc:CTC02069 septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; IMG reference gene:2504784066; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD.
 
 
 0.999
AEE14316.1
COGs: COG1792 Cell shape-determining protein; InterPro IPR007221; KEGG: pmx:PERMA_0056 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; IMG reference gene:2504784062; PFAM: rod shape-determining protein MreC.
  
  
 0.971
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
  
 0.963
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.909
AEE14315.1
Cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: rod shape-determining protein MreB; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl; IMG reference gene:2504784061; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.
  
  
 0.903
AEE14318.1
Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: dtu:Dtur_1401 penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504784064; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
  
  
 0.863
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.838
AEE14322.1
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: dap:Dacet_1268 rod shape-determining protein RodA; PFAM: Cell cycle protein; SPTR: Rod shape-determining protein RodA; IMG reference gene:2504784068; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family.
     
 0.823
AEE14317.1
Hypothetical protein; IMG reference gene:2504784063.
       0.773
AEE14323.1
Protein of unknown function DUF6 transmembrane; InterPro IPR000620; KEGG: tsi:TSIB_1760 permease, drug/metabolite transporter (DMT) superfamily; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Permease, drug/metabolite transporter (DMT) superfamily; IMG reference gene:2504784069; PFAM: EamA-like transporter family.
       0.773
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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