Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (336 aa)    
Predicted Functional Partners:
AEE14438.1
L-fuculose-phosphate aldolase; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: tsi:TSIB_0907 L-fuculose phosphate aldolase; PFAM: Class II aldolase/adducin, N-terminal; PRIAM: L-fuculose-phosphate aldolase; SPTR: Fuculose-1-phosphate aldolase; IMG reference gene:2504784197; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
  
 0.965
AEE14627.1
Multi-copper polyphenol oxidoreductase, laccase; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: sse:Ssed_3498 hypothetical protein; PFAM: Multi-copper polyphenol oxidoreductase, laccase; SPTR: Putative uncharacterized protein; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; IMG reference gene:2504784395; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.901
AEE14437.1
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
  
 0.821
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
     
 0.787
AEE14436.1
UPF0235 protein yggU; HAMAP: Protein of unknown function DUF167; InterPro IPR003746; KEGG: brm:Bmur_1218 protein of unknown function DUF167; PFAM: Protein of unknown function DUF167; SPTR: UPF0235 protein Bmur_1218; IMG reference gene:2504784195; PFAM: Uncharacterised ACR, YggU family COG1872; TIGRFAM: TIGR00251 family protein; Belongs to the UPF0235 family.
       0.714
AEE14433.1
Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.709
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.705
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
    0.704
AEE14435.1
DivIVA domain protein; InterPro IPR007793:IPR019933; KEGG: aoe:Clos_1411 DivIVA family protein; PFAM: DivIVA; SPTR: DivIVA family protein; TIGRFAM: DivIVA domain; IMG reference gene:2504784194; PFAM: DivIVA protein; TIGRFAM: DivIVA domain.
       0.697
AEE14431.1
ABC-type transporter, integral membrane subunit; COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: ddf:DEFDS_0133 peptide/nickel ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Peptide/nickel ABC transporter, permease; IMG reference gene:2504784190; PFAM: Binding-protein-dependent transport system inner membrane component.
  
    0.693
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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