STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE14538.1Asparaginase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: dhd:Dhaf_3068 asparaginase; PFAM: Asparaginase/glutaminase; PRIAM: Asparaginase; SPTR: Asparaginase; IMG reference gene:2504784303; PFAM: Asparaginase; TIGRFAM: L-asparaginases, type II. (326 aa)    
Predicted Functional Partners:
AEE15123.1
COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR000362; KEGG: mta:Moth_1273 aspartate ammonia-lyase; PFAM: Fumarate lyase; PRIAM: Aspartate ammonia-lyase; SPTR: Fumarate lyase; IMG reference gene:2504784923; PFAM: Lyase.
 
 
 0.974
AEE15320.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
   
 
 0.912
AEE14673.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: cst:CLOST_1222 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase class I and II; IMG reference gene:2504784442; PFAM: Aminotransferase class I and II.
    
 0.910
argG
COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: toc:Toce_0156 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; IMG reference gene:2504783864; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.909
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: sfu:Sfum_2090 aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504784111; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamo [...]
     
  0.900
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
  0.900
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.839
AEE13878.1
COGs: COG0527 Aspartokinase; InterPro IPR005260:IPR001341:IPR001048:IPR002912; KEGG: adg:Adeg_0884 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; IMG reference gene:2504783596; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
     
 0.811
AEE14539.1
Amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: ckr:CKR_0577 hypothetical protein; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase; IMG reference gene:2504784304; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase.
       0.547
AEE14537.1
Diguanylate cyclase with PAS/PAC and GAF sensors; COGs: COG2199 FOG: GGDEF domain; InterPro IPR003018:IPR013767:IPR000160:IPR000014; KEGG: tte:TTE1100 diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate cyclase, predicted; PAS fold; GAF; SMART: Diguanylate cyclase, predicted; GAF; PAS; SPTR: Putative diguanylate cyclase/phosphodiesterase; TIGRFAM: Diguanylate cyclase, predicted; PAS; IMG reference gene:2504784302; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
       0.535
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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