STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE14899.14-oxalocrotonate tautomerase; InterPro IPR004370; KEGG: pth:PTH_1705 hypothetical protein; PFAM: 4-oxalocrotonate tautomerase; SPTR: Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; IMG reference gene:2504784691; PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme. (61 aa)    
Predicted Functional Partners:
AEE14898.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: ferric-uptake regulator; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; IMG reference gene:2504784690; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
     
 0.774
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.773
AEE14897.1
KEGG: ddf:DEFDS_1165 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504784689.
       0.598
hisI
COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Histidine biosynthesis bifunctional protein hisIE; InterPro IPR008179:IPR002496; KEGG: dtu:Dtur_1127 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504784751; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophospho [...]
       0.412
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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