STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE15000.1COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: mvu:Metvu_0975 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504784796; PFAM: Periplasmic binding protein. (362 aa)    
Predicted Functional Partners:
AEE14998.1
Phosphonate-transporting ATPase; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: tte:TTE1867 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; IMG reference gene:2504784794; PFAM: ABC transporter.
 
 
 0.998
AEE14999.1
ABC-type transporter, integral membrane subunit; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: tte:TTE1868 ABC-type cobalamin/Fe3+-siderophores transport systems, permease components; PFAM: Bacterial transport system permease protein; SPTR: ABC-type cobalamin/Fe3+-siderophores transport systems, permease components; IMG reference gene:2504784795; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.998
AEE15001.1
Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; KEGG: mmz:MmarC7_1780 cobyrinic acid ac-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase; IMG reference gene:2504784797; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
     0.879
AEE14997.1
Methyltransferase type 12; InterPro IPR013217; KEGG: cki:Calkr_2324 methyltransferase type 11; PFAM: Methyltransferase type 12; SPTR: Methyltransferase type 11; IMG reference gene:2504784793; PFAM: Methyltransferase domain.
 
     0.787
AEE15087.1
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878:IPR003754; KEGG: slp:Slip_1426 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; IMG reference gene:2504784886; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin [...]
     
 0.662
AEE14028.1
COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: cte:CT1717 tungsten formylmethanofuran dehydrogenase, subunit E, putative; PFAM: Formylmethanofuran dehydrogenase, subunit E region; SPTR: Putative uncharacterized protein; IMG reference gene:2504783761; PFAM: Prokaryotic dksA/traR C4-type zinc finger; FmdE, Molybdenum formylmethanofuran dehydrogenase operon.
 
    0.647
AEE14630.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.554
AEE15002.1
2-hydroxy-3-oxopropionate reductase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: bao:BAMF_1472 putative beta-hydroxyacid dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: Putative beta-hydroxyacid dehydrogenase; IMG reference gene:2504784798; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase.
  
    0.473
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
    0.466
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.464
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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