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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE15273.1COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: str:Sterm_3089 glycosyl transferase family 9; PFAM: Glycosyl transferase, family 9; SPTR: Glycosyl transferase family 9; IMG reference gene:2504785079; PFAM: Glycosyltransferase family 9 (heptosyltransferase). (339 aa)    
Predicted Functional Partners:
AEE15274.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: mpl:Mpal_0362 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2504785080; PFAM: Glycosyl transferases group 1.
 
    0.849
AEE14912.1
rfaE bifunctional protein; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011913:IPR011611; KEGG: ddf:DEFDS_0511 ADP-heptose synthase; PFAM: Carbohydrate/purine kinase; SPTR: ADP-heptose synthase; TIGRFAM: RfaE bifunctional protein, domain I; IMG reference gene:2504784704; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I.
 
  
 0.792
AEE14911.1
Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
 
  
 0.790
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.776
AEE14480.1
COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: has:Halsa_2129 glycosyl transferase family 9; PFAM: Glycosyl transferase, family 9; SPTR: Glycosyl transferase family 9; IMG reference gene:2504784243; PFAM: Glycosyltransferase family 9 (heptosyltransferase).
  
     0.775
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
       0.773
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.701
AEE15270.1
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
       0.701
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
 
   
 0.643
AEE15268.1
Hypothetical protein; IMG reference gene:2504785074.
       0.599
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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