STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE15283.1Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dhd:Dhaf_1230 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504785089; PFAM: Response regulator receiver domain; Bacteri [...] (231 aa)    
Predicted Functional Partners:
AEE15282.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003660:IPR003594; KEGG: ATPase ATP-binding domain-containing protein; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; SMART: HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Histidine kinase; IMG reference gene:2504785088; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.961
AEE15175.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003660:IPR011712:IPR003594; KEGG: nth:Nther_0649 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504784976; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.931
AEE15281.1
COGs: COG3221 ABC-type phosphate/phosphonate transport system periplasmic component; InterPro IPR005770; KEGG: cni:Calni_0643 phosphonate abc transporter, periplasmic phosphonate-binding protein; SPTR: Phosphonate ABC transporter, periplasmic phosphonate-binding protein; TIGRFAM: Phosphonate-binding periplasmic protein; IMG reference gene:2504785087; PFAM: NMT1/THI5 like; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein.
  
    0.782
AEE15280.1
COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: hla:Hlac_1706 UspA domain protein; PFAM: UspA; SPTR: UspA domain protein; IMG reference gene:2504785086; PFAM: Universal stress protein family.
  
    0.776
AEE15278.1
KEGG: dma:DMR_10840 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504785084.
       0.762
AEE15279.1
Protein of unknown function DUF81; COGs: COG0730 permease; InterPro IPR002781; KEGG: dba:Dbac_2673 protein of unknown function DUF81; PFAM: Protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2504785085; PFAM: Sulfite exporter TauE/SafE.
       0.762
AEE14061.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR000160:IPR001633:IPR013767:IPR 003018:IPR013655; KEGG: nis:NIS_0136 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold-3; GAF; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PAS; IMG reference gene:2504783796; PFA [...]
  
 
 0.692
AEE14747.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001610:IPR001633:IPR 013655:IPR013767:IPR003018; KEGG: ddf:DEFDS_1856 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold; PAS fold-3; GAF; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS; PAC motif; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PAS; IMG reference gene:2504784532; PFAM: EAL domain; GGDEF domain; PAS fold; TIGRF [...]
  
 
 0.692
AEE15277.1
UspA domain-containing protein; InterPro IPR006016; KEGG: iho:Igni_0456 UspA domain-containing protein; PFAM: UspA; SPTR: UspA domain protein; IMG reference gene:2504785083; PFAM: Universal stress protein family.
  
    0.615
AEE14826.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000014:IPR000160:IPR001633:IPR013767; KEGG: ddf:DEFDS_1856 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PAS; IMG reference gene:2504784615; PFAM: EAL domain; GGDEF domain; PAS fold; TIGR [...]
  
 
 0.592
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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