STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trkATrkA-C domain protein; Identified by match to protein family HMM PF02080; match to protein family HMM PF02254. (227 aa)    
Predicted Functional Partners:
MALL_0028
Cation transport protein; Identified by match to protein family HMM PF02386.
 
 
 0.992
MALL_0142
Phosphatidylinositol-specific phospholipase C, X domain protein; Identified by match to protein family HMM PF00388.
       0.768
pstA
Phosphate ABC transporter, permease protein PstA; Identified by match to protein family HMM PF00528.
  
  
 0.567
MALL_0144
Dihydroxyacetone kinase, phosphotransfer subunit; Identified by match to protein family HMM PF03610; match to protein family HMM TIGR02364.
       0.518
dhaL
Dihydroxyacetone kinase, L subunit; Identified by match to protein family HMM PF02734; match to protein family HMM TIGR02365.
       0.518
dhaK
Dihydroxyacetone kinase, DhaK subunit; Identified by match to protein family HMM PF02733; match to protein family HMM TIGR02363.
       0.518
dnaJ
Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
   
 
 0.460
nfo
Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
  
 0.455
MALL_0233
ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
  
  
 0.447
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.443
Your Current Organism:
Mycoplasma alligatoris
NCBI taxonomy Id: 747682
Other names: M. alligatoris A21JP2, Mycoplasma alligatoris A21JP2, Mycoplasma alligatoris ATCC 700619, Mycoplasma alligatoris str. A21JP2, Mycoplasma alligatoris strain A21JP2
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