Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family.
  
 0.964
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
 
 
 0.950
MALL_0116
Hypothetical protein; Identified by glimmer; putative.
  
 0.923
fba
Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859.
  
 
 0.908
MALL_0700
Putative transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; Belongs to the transketolase family.
  
 0.891
MALL_0071
Hexose kinase, 1-phosphofructokinase family; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family.
     
 0.870
MALL_0103
Putative 2-deoxy-D-gluconate 3-dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00106.
   
 0.858
MALL_0645
Conserved domain protein.
    
 0.847
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.802
MALL_0725
Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain protein; Identified by match to protein family HMM PF02800.
 
  
 0.798
Your Current Organism:
Mycoplasma alligatoris
NCBI taxonomy Id: 747682
Other names: M. alligatoris A21JP2, Mycoplasma alligatoris A21JP2, Mycoplasma alligatoris ATCC 700619, Mycoplasma alligatoris str. A21JP2, Mycoplasma alligatoris strain A21JP2
Server load: low (12%) [HD]