| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MALL_0282 | thiI | MALL_0282 | MALL_0283 | Conserved domain protein. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.779 |
| MALL_0282 | whiA | MALL_0282 | MALL_0281 | Conserved domain protein. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.557 |
| MALL_0730 | pheT | MALL_0730 | MALL_0821 | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF03483; match to protein family HMM TIGR00472. | 0.768 |
| MALL_0730 | thiG | MALL_0730 | MALL_0846 | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.435 |
| MALL_0730 | thiI | MALL_0730 | MALL_0283 | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.474 |
| MALL_0730 | truB | MALL_0730 | MALL_0318 | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | tRNA pseudouridine synthase B; Identified by match to protein family HMM PF01509; match to protein family HMM TIGR00431; Belongs to the pseudouridine synthase TruB family. | 0.589 |
| MALL_0730 | whiA | MALL_0730 | MALL_0281 | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.491 |
| pheT | MALL_0730 | MALL_0821 | MALL_0730 | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF03483; match to protein family HMM TIGR00472. | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | 0.768 |
| pheT | thiI | MALL_0821 | MALL_0283 | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF03483; match to protein family HMM TIGR00472. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.577 |
| pheT | trmU | MALL_0821 | MALL_0277 | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF03483; match to protein family HMM TIGR00472. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.632 |
| pheT | truB | MALL_0821 | MALL_0318 | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF03483; match to protein family HMM TIGR00472. | tRNA pseudouridine synthase B; Identified by match to protein family HMM PF01509; match to protein family HMM TIGR00431; Belongs to the pseudouridine synthase TruB family. | 0.558 |
| thiG | MALL_0730 | MALL_0846 | MALL_0730 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | 0.435 |
| thiG | thiI | MALL_0846 | MALL_0283 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.624 |
| thiI | MALL_0282 | MALL_0283 | MALL_0282 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | Conserved domain protein. | 0.779 |
| thiI | MALL_0730 | MALL_0283 | MALL_0730 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 5'-3' exonuclease, SAM domain protein; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739. | 0.474 |
| thiI | pheT | MALL_0283 | MALL_0821 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF03483; match to protein family HMM TIGR00472. | 0.577 |
| thiI | thiG | MALL_0283 | MALL_0846 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.624 |
| thiI | trmU | MALL_0283 | MALL_0277 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.615 |
| thiI | truB | MALL_0283 | MALL_0318 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | tRNA pseudouridine synthase B; Identified by match to protein family HMM PF01509; match to protein family HMM TIGR00431; Belongs to the pseudouridine synthase TruB family. | 0.431 |
| thiI | whiA | MALL_0283 | MALL_0281 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.611 |