| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MALL_0151 | tdk | MALL_0151 | MALL_0724 | Identified by match to protein family HMM PF03372. | Thymidine kinase; Identified by match to protein family HMM PF00265. | 0.851 |
| MALL_0151 | tmk | MALL_0151 | MALL_0397 | Identified by match to protein family HMM PF03372. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.859 |
| MALL_0326 | MALL_0477 | MALL_0326 | MALL_0477 | 5'-nucleotidase, C-terminal domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Cytidine and deoxycytidylate deaminase zinc-binding region; Identified by match to protein family HMM PF00383. | 0.897 |
| MALL_0326 | tdk | MALL_0326 | MALL_0724 | 5'-nucleotidase, C-terminal domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Thymidine kinase; Identified by match to protein family HMM PF00265. | 0.896 |
| MALL_0326 | thyA | MALL_0326 | MALL_0418 | 5'-nucleotidase, C-terminal domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.897 |
| MALL_0326 | tmk | MALL_0326 | MALL_0397 | 5'-nucleotidase, C-terminal domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.902 |
| MALL_0399 | dnaX | MALL_0399 | MALL_0400 | DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase III, subunit gamma and tau; Identified by match to protein family HMM PF00004; match to protein family HMM TIGR02397. | 0.857 |
| MALL_0399 | tmk | MALL_0399 | MALL_0397 | DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.840 |
| MALL_0399 | yraL | MALL_0399 | MALL_0395 | DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.819 |
| MALL_0413 | MALL_0415 | MALL_0413 | MALL_0415 | Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
| MALL_0413 | thyA | MALL_0413 | MALL_0418 | Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.472 |
| MALL_0413 | tmk | MALL_0413 | MALL_0397 | Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.912 |
| MALL_0415 | MALL_0413 | MALL_0415 | MALL_0413 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268. | 0.999 |
| MALL_0415 | thyA | MALL_0415 | MALL_0418 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.846 |
| MALL_0415 | tmk | MALL_0415 | MALL_0397 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.924 |
| MALL_0477 | MALL_0326 | MALL_0477 | MALL_0326 | Cytidine and deoxycytidylate deaminase zinc-binding region; Identified by match to protein family HMM PF00383. | 5'-nucleotidase, C-terminal domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 0.897 |
| MALL_0477 | tdk | MALL_0477 | MALL_0724 | Cytidine and deoxycytidylate deaminase zinc-binding region; Identified by match to protein family HMM PF00383. | Thymidine kinase; Identified by match to protein family HMM PF00265. | 0.952 |
| MALL_0477 | thyA | MALL_0477 | MALL_0418 | Cytidine and deoxycytidylate deaminase zinc-binding region; Identified by match to protein family HMM PF00383. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.923 |
| MALL_0477 | tmk | MALL_0477 | MALL_0397 | Cytidine and deoxycytidylate deaminase zinc-binding region; Identified by match to protein family HMM PF00383. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.909 |
| dnaX | MALL_0399 | MALL_0400 | MALL_0399 | DNA polymerase III, subunit gamma and tau; Identified by match to protein family HMM PF00004; match to protein family HMM TIGR02397. | DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.857 |
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