Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
polCDNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1432 aa)    
Predicted Functional Partners:
MALL_0731
Putative DNA polymerase III DnaE; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.
    
 0.886
dnaX
DNA polymerase III, subunit gamma and tau; Identified by match to protein family HMM PF00004; match to protein family HMM TIGR02397.
  
 
 0.878
dnaN
DNA polymerase III, beta subunit; Identified by match to protein family HMM PF00712; match to protein family HMM PF02767; match to protein family HMM PF02768; match to protein family HMM TIGR00663.
    
 0.872
MALL_0832
DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144.
    
 0.872
MALL_0396
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.842
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
 
     0.759
ligA
DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
   
 
 0.678
MALL_0262
Putative ATP-dependent DNA helicase PcrA; Identified by match to protein family HMM PF00580.
  
 
 0.651
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
    
 0.645
cdsA
Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148.
       0.622
Your Current Organism:
Mycoplasma alligatoris
NCBI taxonomy Id: 747682
Other names: M. alligatoris A21JP2, Mycoplasma alligatoris A21JP2, Mycoplasma alligatoris ATCC 700619, Mycoplasma alligatoris str. A21JP2, Mycoplasma alligatoris strain A21JP2
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