| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFQ05491.1 | cysE | HMPREF9436_03008 | HMPREF9436_02283 | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | KEGG: cce:Ccel_3325 5.5e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.884 |
| EFQ05491.1 | glyA | HMPREF9436_03008 | HMPREF9436_01530 | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.562 |
| EFQ05491.1 | ilvA | HMPREF9436_03008 | HMPREF9436_01619 | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | KEGG: pdi:BDI_1979 2.7e-133 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 8.96. | 0.930 |
| EFQ05491.1 | metA | HMPREF9436_03008 | HMPREF9436_03294 | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.925 |
| EFQ05491.1 | sdaAA | HMPREF9436_03008 | HMPREF9436_00007 | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_1459 2.4e-93 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752. | 0.862 |
| EFQ05491.1 | sdaAB | HMPREF9436_03008 | HMPREF9436_00006 | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_1460 9.4e-69 L-serine dehydratase, iron-sulfur-dependent, beta subunit; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96. | 0.862 |
| EFQ05491.1 | thrB | HMPREF9436_03008 | HMPREF9436_03009 | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.997 |
| EFQ07277.1 | ilvA | HMPREF9436_01205 | HMPREF9436_01619 | Glyoxalase family protein; KEGG: ooe:OEOE_1705 5.0e-31 methylmalonyl-CoA epimerase; Psort location: Cytoplasmic, score: 8.96. | KEGG: pdi:BDI_1979 2.7e-133 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 8.96. | 0.861 |
| EFQ07277.1 | pdxB | HMPREF9436_01205 | HMPREF9436_00866 | Glyoxalase family protein; KEGG: ooe:OEOE_1705 5.0e-31 methylmalonyl-CoA epimerase; Psort location: Cytoplasmic, score: 8.96. | 4-phosphoerythronate dehydrogenase; KEGG: shw:Sputw3181_3170 2.8e-69 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; K00018 glycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | 0.831 |
| EFQ07277.1 | sdaAA | HMPREF9436_01205 | HMPREF9436_00007 | Glyoxalase family protein; KEGG: ooe:OEOE_1705 5.0e-31 methylmalonyl-CoA epimerase; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_1459 2.4e-93 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752. | 0.851 |
| EFQ07277.1 | sdaAB | HMPREF9436_01205 | HMPREF9436_00006 | Glyoxalase family protein; KEGG: ooe:OEOE_1705 5.0e-31 methylmalonyl-CoA epimerase; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_1460 9.4e-69 L-serine dehydratase, iron-sulfur-dependent, beta subunit; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96. | 0.851 |
| EFQ07968.1 | glyA | HMPREF9436_00506 | HMPREF9436_01530 | KEGG: eel:EUBELI_00350 5.9e-60 phosphoglycerate mutase; K01834 phosphoglycerate mutase; Psort location: Cytoplasmic, score: 8.96. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.867 |
| EFQ07968.1 | sdaAA | HMPREF9436_00506 | HMPREF9436_00007 | KEGG: eel:EUBELI_00350 5.9e-60 phosphoglycerate mutase; K01834 phosphoglycerate mutase; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_1459 2.4e-93 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752. | 0.854 |
| EFQ07968.1 | sdaAB | HMPREF9436_00506 | HMPREF9436_00006 | KEGG: eel:EUBELI_00350 5.9e-60 phosphoglycerate mutase; K01834 phosphoglycerate mutase; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_1460 9.4e-69 L-serine dehydratase, iron-sulfur-dependent, beta subunit; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96. | 0.854 |
| cysE | EFQ05491.1 | HMPREF9436_02283 | HMPREF9436_03008 | KEGG: cce:Ccel_3325 5.5e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: ate:Athe_1959 6.2e-100 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.96. | 0.884 |
| cysE | glyA | HMPREF9436_02283 | HMPREF9436_01530 | KEGG: cce:Ccel_3325 5.5e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.881 |
| cysE | ilvA | HMPREF9436_02283 | HMPREF9436_01619 | KEGG: cce:Ccel_3325 5.5e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: pdi:BDI_1979 2.7e-133 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 8.96. | 0.867 |
| cysE | sdaAA | HMPREF9436_02283 | HMPREF9436_00007 | KEGG: cce:Ccel_3325 5.5e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: cpy:Cphy_1459 2.4e-93 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752. | 0.864 |
| cysE | sdaAB | HMPREF9436_02283 | HMPREF9436_00006 | KEGG: cce:Ccel_3325 5.5e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: cpy:Cphy_1460 9.4e-69 L-serine dehydratase, iron-sulfur-dependent, beta subunit; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96. | 0.864 |
| cysE | thrB | HMPREF9436_02283 | HMPREF9436_03009 | KEGG: cce:Ccel_3325 5.5e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.879 |