Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFQ06471.1Putative stage V sporulation protein AC; Psort location: CytoplasmicMembrane, score: 10.00. (153 aa)    
Predicted Functional Partners:
spoVAD
Stage V sporulation protein AD.
 
  
 0.975
EFQ06469.1
Putative stage V sporulation protein AE; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.949
EFQ06466.1
Putative GPR endopeptidase; KEGG: cpr:CPR_2013 3.2e-36 gpr; germination protease K06012.
  
  
 0.854
EFQ05579.1
Putative sporulation transcriptional regulator SpoIIID.
  
   
 0.813
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.810
spoIVB
SpoIVB peptidase; KEGG: ckr:CKR_1133 5.5e-64 hypothetical protein; K06399 stage IV sporulation protein B.
  
   
 0.808
spoIVA
Stage IV sporulation protein A; Psort location: Cytoplasmic, score: 8.96.
  
   
 0.808
EFQ05702.1
STAS domain protein; KEGG: npu:Npun_F4337 0.0028 anti-sigma-factor antagonist and sugar transfersase.
 
   
 0.807
EFQ06912.1
Hypothetical protein.
  
  
 0.798
EFQ07242.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.788
Your Current Organism:
Faecalibacterium prausnitzii KLE1255
NCBI taxonomy Id: 748224
Other names: F. cf. prausnitzii KLE1255, Faecalibacterium cf. prausnitzii KLE1255, Faecalibacterium cf. prausnitzii str. KLE1255, Faecalibacterium cf. prausnitzii strain KLE1255
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