STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tolCType I secretion outer membrane protein TolC. (433 aa)    
Predicted Functional Partners:
acrA-4
Cation/multidrug efflux system, membrane-fusion protein AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.976
hlyD
HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.973
acrA-3
Cation/multidrug efflux system, membrane-fusion protein AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.963
NH8B_2665
RND efflux system, membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.963
acrB-3
Cation/multidrug efflux pump AcrB.
  
 0.938
NH8B_2357
Cation/multidrug efflux system, outer membrane channel TolC.
     
 0.907
acrA
Efflux transporter, membrane fusion protein AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.886
macB
ABC transporter, ATP-binding/permease protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.831
acrB
Transmembrane drug efflux protein AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.771
NH8B_3820
Type I secretion system ATPase.
  
  
 0.769
Your Current Organism:
Pseudogulbenkiania sp. NH8B
NCBI taxonomy Id: 748280
Other names: P. sp. NH8B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.