| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NH8B_1211 | ubiA | NH8B_1211 | NH8B_0791 | Oxidoreductase, FAD-binding. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.693 |
| NH8B_1211 | ubiD | NH8B_1211 | NH8B_0434 | Oxidoreductase, FAD-binding. | 3-octaprenyl-4- hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.921 |
| NH8B_1211 | ubiX | NH8B_1211 | NH8B_3336 | Oxidoreductase, FAD-binding. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.921 |
| NH8B_2727 | ubiX | NH8B_2727 | NH8B_3336 | PrpF protein. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.800 |
| NH8B_3331 | NH8B_3333 | NH8B_3331 | NH8B_3333 | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | ATP-binding protein; Displays ATPase and GTPase activities. | 0.974 |
| NH8B_3331 | NH8B_3334 | NH8B_3331 | NH8B_3334 | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | Protein of unknown function; DUF1312. | 0.817 |
| NH8B_3331 | NH8B_3335 | NH8B_3331 | NH8B_3335 | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | Heptaprenyl diphosphate synthase component I; K00805. | 0.817 |
| NH8B_3331 | hprK | NH8B_3331 | NH8B_3332 | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). | 0.944 |
| NH8B_3331 | nnrD | NH8B_3331 | NH8B_3337 | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.832 |
| NH8B_3331 | ubiX | NH8B_3331 | NH8B_3336 | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.820 |
| NH8B_3333 | NH8B_3331 | NH8B_3333 | NH8B_3331 | ATP-binding protein; Displays ATPase and GTPase activities. | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | 0.974 |
| NH8B_3333 | NH8B_3334 | NH8B_3333 | NH8B_3334 | ATP-binding protein; Displays ATPase and GTPase activities. | Protein of unknown function; DUF1312. | 0.820 |
| NH8B_3333 | NH8B_3335 | NH8B_3333 | NH8B_3335 | ATP-binding protein; Displays ATPase and GTPase activities. | Heptaprenyl diphosphate synthase component I; K00805. | 0.819 |
| NH8B_3333 | hprK | NH8B_3333 | NH8B_3332 | ATP-binding protein; Displays ATPase and GTPase activities. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). | 0.843 |
| NH8B_3333 | nnrD | NH8B_3333 | NH8B_3337 | ATP-binding protein; Displays ATPase and GTPase activities. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.850 |
| NH8B_3333 | ubiX | NH8B_3333 | NH8B_3336 | ATP-binding protein; Displays ATPase and GTPase activities. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.821 |
| NH8B_3334 | NH8B_3331 | NH8B_3334 | NH8B_3331 | Protein of unknown function; DUF1312. | PTS IIA-like nitrogen-regulatory protein PtsN; K02806. | 0.817 |
| NH8B_3334 | NH8B_3333 | NH8B_3334 | NH8B_3333 | Protein of unknown function; DUF1312. | ATP-binding protein; Displays ATPase and GTPase activities. | 0.820 |
| NH8B_3334 | NH8B_3335 | NH8B_3334 | NH8B_3335 | Protein of unknown function; DUF1312. | Heptaprenyl diphosphate synthase component I; K00805. | 0.989 |
| NH8B_3334 | hprK | NH8B_3334 | NH8B_3332 | Protein of unknown function; DUF1312. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). | 0.820 |