| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB40065.1 | AGB40704.1 | Halha_0039 | Halha_0731 | Actin-like ATPase involved in cell division; PFAM: StbA protein; TIGRFAM: PRTRC system protein D. | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | 0.508 |
| AGB40065.1 | clpP | Halha_0039 | Halha_2028 | Actin-like ATPase involved in cell division; PFAM: StbA protein; TIGRFAM: PRTRC system protein D. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.508 |
| AGB40065.1 | dnaJ | Halha_0039 | Halha_1897 | Actin-like ATPase involved in cell division; PFAM: StbA protein; TIGRFAM: PRTRC system protein D. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.963 |
| AGB40065.1 | groL | Halha_0039 | Halha_0304 | Actin-like ATPase involved in cell division; PFAM: StbA protein; TIGRFAM: PRTRC system protein D. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.806 |
| AGB40065.1 | grpE | Halha_0039 | Halha_1899 | Actin-like ATPase involved in cell division; PFAM: StbA protein; TIGRFAM: PRTRC system protein D. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.939 |
| AGB40065.1 | hrcA | Halha_0039 | Halha_1900 | Actin-like ATPase involved in cell division; PFAM: StbA protein; TIGRFAM: PRTRC system protein D. | Heat shock gene repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.696 |
| AGB40530.1 | AGB40704.1 | Halha_0556 | Halha_0731 | PFAM: StbA protein. | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | 0.508 |
| AGB40530.1 | clpP | Halha_0556 | Halha_2028 | PFAM: StbA protein. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.508 |
| AGB40530.1 | dnaJ | Halha_0556 | Halha_1897 | PFAM: StbA protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.963 |
| AGB40530.1 | groL | Halha_0556 | Halha_0304 | PFAM: StbA protein. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.806 |
| AGB40530.1 | grpE | Halha_0556 | Halha_1899 | PFAM: StbA protein. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.939 |
| AGB40530.1 | hrcA | Halha_0556 | Halha_1900 | PFAM: StbA protein. | Heat shock gene repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.696 |
| AGB40704.1 | AGB40065.1 | Halha_0731 | Halha_0039 | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | Actin-like ATPase involved in cell division; PFAM: StbA protein; TIGRFAM: PRTRC system protein D. | 0.508 |
| AGB40704.1 | AGB40530.1 | Halha_0731 | Halha_0556 | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | PFAM: StbA protein. | 0.508 |
| AGB40704.1 | dnaJ | Halha_0731 | Halha_1897 | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.581 |
| AGB40704.1 | dnaK | Halha_0731 | Halha_1898 | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.645 |
| AGB40704.1 | groL | Halha_0731 | Halha_0304 | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.638 |
| AGB40704.1 | grpE | Halha_0731 | Halha_1899 | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.592 |
| AGB40704.1 | hrcA | Halha_0731 | Halha_1900 | Protease subunit of ATP-dependent protease; PFAM: Clp protease. | Heat shock gene repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.689 |
| AGB41812.1 | dnaJ | Halha_1901 | Halha_1897 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.515 |
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