Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB42038.1Hypothetical protein. (1250 aa)    
Predicted Functional Partners:
AGB42039.1
Hypothetical protein.
 
     0.957
AGB42040.1
PAPS reductase/FAD synthetase family protein; PFAM: Phosphoadenosine phosphosulfate reductase family.
 
     0.953
AGB42044.1
DNA phosphorothioation system restriction enzyme; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; TIGRFAM: DNA phosphorothioation system restriction enzyme.
 
    0.873
AGB42042.1
TIGRFAM: DNA sulfur modification protein DndD.
 
     0.842
AGB42037.1
PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein.
 
     0.816
AGB40775.1
PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase; manually curated; non-canonical start codon.
 
     0.769
AGB40921.1
Hypothetical protein.
  
     0.751
AGB41448.1
ABC-type sugar transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding protein.
  
     0.732
AGB40304.1
Hypothetical protein.
  
     0.724
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.710
Your Current Organism:
Halobacteroides halobius
NCBI taxonomy Id: 748449
Other names: H. halobius DSM 5150, Halobacteroides halobius ATCC 35273, Halobacteroides halobius DSM 5150, Halobacteroides halobius MD-1, Halobacteroides halobius str. DSM 5150, Halobacteroides halobius strain DSM 5150
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