Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AGB42146.1PFAM: S23 ribosomal protein. (116 aa)    
Predicted Functional Partners:
AGB41468.1
Type II secretory pathway, component PulK; PFAM: General secretion pathway protein K.
  
 
 0.776
AGB41727.1
PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB; general secretory pathway protein E.
  
 
 0.725
AGB42155.1
Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein); PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
  
  
 0.608
AGB40491.1
Type II secretory pathway, component PulF; PFAM: Bacterial type II secretion system protein F domain.
  
  
 0.577
AGB41725.1
Type II secretory pathway, component PulF; PFAM: Bacterial type II secretion system protein F domain; TIGRFAM: general secretion pathway protein F; manually curated; non-canonical start codon.
  
  
 0.577
AGB41822.1
PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.553
csrA
Carbon storage regulator CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
  
    0.515
AGB40616.1
PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
  
 0.471
fliW
Hypothetical protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
       0.443
AGB41723.1
Prepilin signal peptidase PulO-like peptidase; PFAM: Bacterial Peptidase A24 N-terminal domain; Type IV leader peptidase family.
  
  
 0.435
Your Current Organism:
Halobacteroides halobius
NCBI taxonomy Id: 748449
Other names: H. halobius DSM 5150, Halobacteroides halobius ATCC 35273, Halobacteroides halobius DSM 5150, Halobacteroides halobius MD-1, Halobacteroides halobius str. DSM 5150, Halobacteroides halobius strain DSM 5150
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