STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADK15021.12-aminoadipate transaminase; Predicted transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain. (392 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase.
 
  
 0.916
ADK15991.1
Predicted transcriptional regulator containing an aminotransferase domain.
  
  
 
0.910
ADK14990.1
Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.904
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.904
ADK16389.1
D-isomer specific 2-hydroxyacid dehydrogenase.
  
 
  0.904
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.903
gcvPB
Glycine dehydrogenase, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
 
 0.903
ADK15187.1
Predicted Aminotransferase, class I and II family.
  
  
 
0.902
ADK13673.1
Predicted FAD/FMN-containing dehydrogenase.
    
  0.901
ADK14458.1
Predicted FAD/FMN-containing dehydrogenase.
    
  0.901
Your Current Organism:
Clostridium ljungdahlii
NCBI taxonomy Id: 748727
Other names: C. ljungdahlii DSM 13528, Clostridium ljungdahlii DSM 13528, Clostridium ljungdahlii PETC, Clostridium ljungdahlii str. DSM 13528, Clostridium ljungdahlii strain DSM 13528
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