node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fen1 | ZHAS_00005287 | A0A084WBF5 | A0A084VJ76 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AGAP008673-PA-like protein. | 0.877 |
Fen1 | ZHAS_00009763 | A0A084WBF5 | A0A084VVV9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.997 |
Fen1 | ZHAS_00010063 | A0A084WBF5 | A0A084VWL2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AGAP002255-PA-like protein. | 0.956 |
Fen1 | ZHAS_00010574 | A0A084WBF5 | A0A084VXX8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AGAP002522-PA-like protein. | 0.895 |
Fen1 | ZHAS_00010829 | A0A084WBF5 | A0A084VYB2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AGAP009047-PA-like protein. | 0.952 |
Fen1 | ZHAS_00012358 | A0A084WBF5 | A0A084W2G8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AGAP005144-PA-like protein. | 0.892 |
Fen1 | ZHAS_00013239 | A0A084WBF5 | A0A084W501 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AGAP003093-PA-like protein. | 0.954 |
Fen1 | ZHAS_00015251 | A0A084WBF5 | A0A084WAI2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Checkpoint protein; Belongs to the HUS1 family. | 0.877 |
Fen1 | ZHAS_00019780 | A0A084WBF5 | A0A084WNA0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AGAP007477-PA-like protein. | 0.944 |
ZHAS_00005287 | Fen1 | A0A084VJ76 | A0A084WBF5 | AGAP008673-PA-like protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.877 |
ZHAS_00005287 | ZHAS_00009763 | A0A084VJ76 | A0A084VVV9 | AGAP008673-PA-like protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.987 |
ZHAS_00005287 | ZHAS_00010063 | A0A084VJ76 | A0A084VWL2 | AGAP008673-PA-like protein. | AGAP002255-PA-like protein. | 0.991 |
ZHAS_00005287 | ZHAS_00010574 | A0A084VJ76 | A0A084VXX8 | AGAP008673-PA-like protein. | AGAP002522-PA-like protein. | 0.995 |
ZHAS_00005287 | ZHAS_00010829 | A0A084VJ76 | A0A084VYB2 | AGAP008673-PA-like protein. | AGAP009047-PA-like protein. | 0.998 |
ZHAS_00005287 | ZHAS_00012358 | A0A084VJ76 | A0A084W2G8 | AGAP008673-PA-like protein. | AGAP005144-PA-like protein. | 0.998 |
ZHAS_00005287 | ZHAS_00013239 | A0A084VJ76 | A0A084W501 | AGAP008673-PA-like protein. | AGAP003093-PA-like protein. | 0.998 |
ZHAS_00005287 | ZHAS_00013966 | A0A084VJ76 | A0A084W704 | AGAP008673-PA-like protein. | AGAP002669-PA-like protein. | 0.839 |
ZHAS_00005287 | ZHAS_00015251 | A0A084VJ76 | A0A084WAI2 | AGAP008673-PA-like protein. | Checkpoint protein; Belongs to the HUS1 family. | 0.991 |
ZHAS_00005287 | ZHAS_00019780 | A0A084VJ76 | A0A084WNA0 | AGAP008673-PA-like protein. | AGAP007477-PA-like protein. | 0.998 |
ZHAS_00009763 | Fen1 | A0A084VVV9 | A0A084WBF5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.997 |