STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV45294.1COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: sun:SUN_2399 hydrolase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Hydrolase; PFAM: Carbon-nitrogen hydrolase. (239 aa)    
Predicted Functional Partners:
ADV47165.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095: IPR014362: IPR006097: IPR006096; KEGG: sun:SUN_1928 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Glutamate dehydrogenase (NADP+); PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.929
ADV46700.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583: IPR006982: IPR002932: IPR002489: IPR 013838: IPR017932; KEGG: nis:NIS_1201 glutamate synthase (NADPH), large chain; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (NADPH), large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
 0.914
ADV45693.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.909
ADV46699.1
Glutamate synthase (NADPH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006006; KEGG: nis:NIS_1200 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), small chain; TIGRFAM: glutamate synthase, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthases, NADH/NADPH, small subunit.
  
  0.905
ADV46738.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176: IPR004838; KEGG: sun:SUN_1362 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; manually curated; PFAM: Aminotransferase class I and II.
  
 
 0.904
ADV45845.1
ATP-citrate lyase/succinyl-CoA ligase; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810: IPR017440: IPR005811; KEGG: nis:NIS_0653 ATP citrate synthase, subunit 2; PFAM: ATP-citrate lyase/succinyl-CoA ligase; SPTR: ATP citrate synthase, subunit 2; PFAM: CoA-ligase; Citrate synthase.
  
  0.817
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.812
ADV45844.1
ATP citrate lyase subunit 1; COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650; KEGG: sun:SUN_0541 ATP citrate synthase, subunit 1; PFAM: ATP-grasp domain protein; SPTR: ATP citrate synthase, subunit 1; PFAM: ATP-grasp domain.
  
  0.811
ADV45642.1
2-oxoglutarate ferredoxin oxidoreductase, beta subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: ant:Arnit_2141 thiamine pyrophosphate protein domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
   
 
  0.803
ADV46520.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810: IPR010953; KEGG: sun:SUN_2395 citrate synthase; PFAM: Citrate synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
   
 
  0.802
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.