STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV45627.1Fumarase alpha subunit; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646: IPR013838; KEGG: nam:NAMH_1233 fumarate hydratase, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region. (283 aa)    
Predicted Functional Partners:
ADV45628.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: nam:NAMH_1232 C-terminal fumarate hydratase, class I; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; SPTR: C-terminal fumarate hydratase, class I; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region.
 
 0.999
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.991
ADV46565.1
InterPro IPR004224; KEGG: ant:Arnit_2666 fumarate reductase respiratory complex; SPTR: Fumarate reductase respiratory complex; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
  
 
 0.948
ADV45511.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013838: IPR003953: IPR004112: IPR013027; KEGG: sun:SUN_0152 succinate dehydrogenase/fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: flavocytochrome c.
  
 
 0.939
ADV46328.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterProIPR014006: IPR003952: IPR003953: IPR004112: IPR 013027; KEGG: sun:SUN_1200 succinate dehydrogenase/fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E [...]
  
 
 0.939
ADV46564.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR003952: IPR014006; KEGG: ant:Arnit_2667 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subu [...]
  
 
 0.939
ADV46516.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302: IPR015884; KEGG: sdl:Sdel_2195 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 
 0.937
ADV45510.1
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR004489: IPR006058: IPR017900: IPR001041: IPR 017896; KEGG: sun:SUN_0151 succinate dehydrogenase/fumarate reductase, iron-sulfur protein; PFAM: ferredoxin; SPTR: Succinate dehydrogenase/fumarate reductase, iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
 0.934
ADV46327.1
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR004489: IPR001041: IPR017896: IPR006058: IPR 017900; KEGG: sun:SUN_1201 succinate dehydrogenase/fumarate reductase, iron-sulfur protein; PFAM: ferredoxin; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase/fumarate reductase, iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
 0.934
ADV46563.1
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR004489: IPR001041: IPR017896; KEGG: abu:Abu_0299 fumarate reductase iron-sulfur subunit; SPTR: Fumarate reductase, iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
 0.934
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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