STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepAPeptidase M17 leucyl aminopeptidase domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (494 aa)    
Predicted Functional Partners:
ADV45676.1
Xaa-His dipeptidase; COGs: COG2195 Di- and tripeptidase; InterPro IPR001160: IPR002933; KEGG: sun:SUN_1808 aminoacyl-histidine dipeptidase; PFAM: peptidase M20; PRIAM: Xaa-His dipeptidase; SPTR: Aminoacyl-histidine dipeptidase; PFAM: Peptidase family M20/M25/M40; TIGRFAM: aminoacyl-histidine dipeptidase.
   
 
 0.918
ADV45953.1
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: pmx:PERMA_0102 gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
 0.914
ADV45954.1
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
  
  0.911
ADV45426.1
COGs: COG0031 Cysteine synthase; InterPro IPR005856: IPR005859: IPR001216: IPR001926; KEGG: mta:Moth_1971 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.836
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.830
ADV46738.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176: IPR004838; KEGG: sun:SUN_1362 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; manually curated; PFAM: Aminotransferase class I and II.
   
  0.816
ADV47253.1
Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: sun:SUN_0398 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; PFAM: Aminotransferase class I and II.
  
 
  0.803
ADV45878.1
KEGG: sun:SUN_0718 S23 ribosomal protein; SPTR: S23 ribosomal protein; PFAM: S23 ribosomal protein.
  
    0.609
ADV46718.1
SNARE associated Golgi protein-like protein; COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: nis:NIS_0705 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: Putative uncharacterized protein; PFAM: SNARE associated Golgi protein.
      0.519
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
  0.518
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
Server load: low (12%) [HD]