STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV46019.1HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0546 phosphatase; InterPro IPR005833: IPR006402: IPR006439: IPR005834; KEGG: sun:SUN_1081 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with thir [...] (220 aa)    
Predicted Functional Partners:
ADV46997.1
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0546 phosphatase; InterPro IPR005834: IPR006402: IPR006439; KEGG: sun:SUN_0197 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif hav [...]
  
  
 
0.927
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
  
  
 
0.922
ADV45475.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: sun:SUN_2130 glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein; SPTR: Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
    
 0.910
ADV45512.1
COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140: IPR006139; KEGG: sun:SUN_0153 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic component; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic component; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
    
  0.901
ADV45529.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR017900: IPR004017: IPR012257: IPR017896; KEGG: nis:NIS_0367 anaerobic glycerol-3-phosphate dehydrogenase subunit C; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Anaerobic glycerol-3-phosphate dehydrogenase subunit C; PFAM: Cysteine-rich domain.
     
  0.900
ADV46017.1
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
     
 0.794
ADV46015.1
Nitrogen-fixing NifU domain protein; InterPro IPR002871; KEGG: sun:SUN_1077 hypothetical protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Putative uncharacterized protein; PFAM: NifU-like N terminal domain.
       0.774
ADV46016.1
KEGG: sun:SUN_1078 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.774
ADV46018.1
Cache domain protein; InterPro IPR004010; KEGG: nis:NIS_1413 general glycosylation pathway protein; PFAM: Cache domain protein; SPTR: General glycosylation pathway protein; PFAM: Cache domain.
       0.773
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.521
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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