STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpCCOGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR001468: IPR013798; KEGG: sun:SUN_1695 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (268 aa)    
Predicted Functional Partners:
trpF
COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: sun:SUN_2155 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family.
 
 0.999
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 0.999
ADV45842.1
COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR017926: IPR006220: IPR011702: IPR001317: IPR 006221: IPR000991; KEGG: sun:SUN_0539 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: Anthranilate synthase component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
  
 0.998
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.998
trpB-2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.998
ADV46907.1
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999: IPR006805: IPR015890: IPR010916; KEGG: sun:SUN_0471 anthranilate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; SPTR: Anthranilate synthase component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme.
 
 0.997
ADV45553.1
Chorismate binding protein; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890: IPR019999; KEGG: sun:SUN_2069 para-aminobenzoate synthase component I; PFAM: Chorismate binding-like; SPTR: Aminodeoxychorismate synthase subunit I; PFAM: chorismate binding enzyme.
 
 0.972
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
    
 0.808
ADV46064.1
Protein of unknown function UPF0153; InterPro IPR005358; KEGG: sun:SUN_1697 hypothetical protein; PFAM: protein of unknown function UPF0153; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153).
   
   0.628
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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