STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
ADV46261.1Biotin/lipoate A/B protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (193 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
 0.996
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.929
ADV45794.1
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
    
 0.825
ADV46388.1
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198: IPR002347; KEGG: sun:SUN_0717 enoyl-(acyl carrier protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Enoyl-[acyl-carrier protein] reductase (NADH); PFAM: short chain dehydrogenase.
     
  0.800
ADV46257.1
Biotin/lipoyl attachment domain-containing protein; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089: IPR003016: IPR000276: IPR001078; KEGG: sun:SUN_1209 pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain-containing protein of components of various dehydrogenase complexes; SPTR: Pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: 2-oxoacid d [...]
 
 
 0.650
ADV46259.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR012999: IPR013027: IPR004099: IPR000815; KEGG: sun:SUN_1208 pyruvate/2-oxoglutarate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, d [...]
 
  
 0.609
ADV46263.1
COGs: COG3133 Outer membrane lipoprotein; KEGG: nis:NIS_1071 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Rickettsia 17 kDa surface antigen.
       0.596
ADV46865.1
COGs: COG2995 Uncharacterized paraquat-inducible protein A; InterPro IPR007498; KEGG: sun:SUN_1335 hypothetical protein; PFAM: Paraquat-inducible protein A; SPTR: Putative uncharacterized protein; PFAM: Paraquat-inducible protein A.
   
    0.533
ADV46265.1
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: sun:SUN_1276 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase.
       0.506
ADV46264.1
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005852: IPR016066: IPR005844: IPR005845: IPR 005846: IPR005843; KEGG: sun:SUN_1277 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: Phosphogluco [...]
       0.454
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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