STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV46309.1CRISPR-associated helicase, Cas3 family; COGs: COG1203 helicase; InterProIPR006474: IPR014021: IPR001650: IPR011545: IPR 014001; KEGG: cco:CCC13826_1422 CRISPR-associated helicase Cas3 domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: CRISPR-associated helicase Cas3 domain protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: Type III restriction enzyme, res subunit; TIGRFAM: CRISPR-associated helicase Cas3. (725 aa)    
Predicted Functional Partners:
ADV46308.1
CRISPR-associated protein, Cas5h family; InterPro IPR013422; KEGG: cco:CCC13826_1421 CRISPR-associated protein Cas5; SPTR: CRISPR-associated protein Cas5; TIGRFAM: CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Hmari subtype; CRISPR-associated protein Cas5, N-terminal domain.
 
 
 0.976
ADV46307.1
CRISPR-associated protein, Csh2 family; COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482: IPR013419; KEGG: cco:CCC13826_1420 CRISPR-associated protein, Csh2 family; PFAM: CRISPR-associated protein TM1801; SPTR: Crispr-associated protein, Csh2 family; TIGRFAM: CRISPR-associated protein, Csh2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csh2 family.
 
  
 0.960
ADV46312.1
COGs: COG1468 RecB family exonuclease; KEGG: cco:CCC13826_1423 CRISPR-associated protein Cas4; SPTR: CRISPR-associated protein Cas4; PFAM: Domain of unknown function DUF83.
 
  
 0.936
cas1
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.927
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.926
ADV46306.1
CRISPR-associated protein TM1802; InterPro IPR013389; KEGG: ccv:CCV52592_1293 hypothetical protein; PFAM: CRISPR-associated protein TM1802; SPTR: Putative uncharacterized protein; PFAM: CRISPR-associated protein TM1802 (cas_TM1802).
       0.800
ADV46305.1
Protein of unknown function DUF86; InterPro IPR008201; KEGG: sun:SUN_0813 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF86.
       0.773
ADV46304.1
DNA polymerase beta domain protein region; InterPro IPR002934; KEGG: cha:CHAB381_0146 nucleotidyltransferase family protein; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase; PFAM: Nucleotidyltransferase domain.
       0.678
ADV46303.1
Protein of unknown function DUF57; InterPro IPR002743; KEGG: cco:CCC13826_1418 hypothetical protein; PFAM: protein of unknown function DUF57; SPTR: Putative uncharacterized protein; manually curated; PFAM: CRISPR associated protein Cas6; TIGRFAM: CRISPR-associated endoribonuclease Cas6.
     
 0.648
ADV46310.1
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.603
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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