STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV46324.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001638: IPR003661: IPR003594: IPR 004358; KEGG: wsu:WS0850 sensory transduction histidine kinase; PFAM: extracellular solute-binding protein family 3; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: SENSORY TRANSDUCTION HISTIDINE KINASE; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) do [...] (1109 aa)    
Predicted Functional Partners:
ADV46869.1
Histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR001638: IPR003594: IPR004358: IPR005467: IPR 003661; KEGG: wsu:WS0850 sensory transduction histidine kinase; PFAM: extracellular solute-binding protein family 3; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; ATP-binding region ATPase domain protein; SPTR: SENSORY TRANSDUCTION HISTIDINE KINASE; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracellular [...]
 
0.962
ADV46325.1
Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: abu:Abu_0630 two-component response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: DIGUANYLATE CYCLASE; PFAM: Response regulator receiver domain.
 
 
 
 0.885
ADV46190.1
Response regulator receiver and Hpt phospho transfer protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789: IPR008207; KEGG: dat:HRM2_43550 putative two-component system sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver domain protein; PFAM: Response regulator receiver domain; Hpt domain.
 
 
 0.857
ADV46323.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: abu:Abu_1725 DNA-binding response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.813
ADV46868.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR000160; KEGG: dap:Dacet_1843 diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator PleD; TIGRFAM: diguanylate cyclase; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 0.806
ADV45811.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR004358: IPR003661: IPR 003594; KEGG: nis:NIS_1346 two-component sensor histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Two-component sensor histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Nitrate and nitrite sensing; [...]
 
 
 0.802
ADV46885.1
COGs: COG2200 FOG: EAL domain; InterPro IPR001789: IPR001633; KEGG: ant:Arnit_0784 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; response regulator receiver; SMART: EAL domain protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain; Response regulator receiver domain.
 
 0.774
ADV47084.1
ABC transporter related protein; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: nis:NIS_1593 sulfonate/nitrate ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Sulfonate/nitrate ABC transporter, ATP-binding protein; PFAM: ABC transporter.
  
  
 0.774
ADV45677.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: ant:Arnit_1670 winged helix family two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.770
ADV46763.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR004358: IPR 005467; KEGG: sun:SUN_0623 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
   
 0.759
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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